Cushings disease occurs in horses, dogs and even people. However, the symptoms are different, depending on the species. In horses it results in increased hair growth (longer, thicker, curly) whereas in dogs it results in hair loss and even bald spots. The horse version of this illness is called ECD (Equine Cushings Disease).
As a horse ages, there is an increasing tendency for the pituitary gland to develop tumors or to grow too large, resulting in it producing more hormones. This in turn stimulates the adrenal glands to produce additional steroids and when the level of steroids becomes excessive it results in cushings. Since these changes are age related, ECD is most often found in horses over 15 years but has been found in horses as young as seven.
The disease cushings is named after Harvey Cushing, who identified and explained the disease in'21. ECD is simply the equine equivalent of the disease which Dr. Cushing first identified in humans.
Different horses show different symptoms of ECD. The most common symptom is coat changes (longer, thicker, curly, failure to shed in Spring, becoming lighter in color). The heavier coat results in increased sweating as a secondary symptom, due to over-heating, especially in summer. The horse tends to lose muscle in its neck and back, despite increased appetite and eating more, while developing a pendulous abdomen. Diabetes often develops, with an associated increase in water consumption and urination. Laminitis always develops eventually. The horse becomes more prone to infections and slower to heal from external injuries due to a depressed immune system. The natural depressions above the eyes tend to fill in with fat.
Any of these symptoms can be caused by a variety of illnesses other than ECD. Consequently, blood and urine tests are normally used to confirm that the cause is ECD (e.g. by measuring hormone levels and hormone response levels) and to rule out other possible diseases. Studies have shown that many horses with ECD are either not diagnosed or incorrectly diagnosed (the symptoms are incorrectly attributed to a different disease), with the result that they do not receive appropriate treatment.
ECD cannot be cured. However, the hormone levels can be reduced to more normal levels through medication, slowing the progress of the disease. As some of the medications can have serious side effects (e.g. liver disease), one needs to monitor for any such side effects and change the medication accordingly.
One also needs to watch for symptoms of secondary diseases, such as laminitis or diabetes, which are more common in horses with ECD. These need to be treated promptly to prevent them from further damaging the horse's health.
One should also maintain the horse's quality of life by treating any symptoms which make it uncomfortable. For example, if the heavier coat results in the horse becoming too warm, one should clip the coat in spring or summer.
As a horse ages, there is an increasing tendency for the pituitary gland to develop tumors or to grow too large, resulting in it producing more hormones. This in turn stimulates the adrenal glands to produce additional steroids and when the level of steroids becomes excessive it results in cushings. Since these changes are age related, ECD is most often found in horses over 15 years but has been found in horses as young as seven.
The disease cushings is named after Harvey Cushing, who identified and explained the disease in'21. ECD is simply the equine equivalent of the disease which Dr. Cushing first identified in humans.
Different horses show different symptoms of ECD. The most common symptom is coat changes (longer, thicker, curly, failure to shed in Spring, becoming lighter in color). The heavier coat results in increased sweating as a secondary symptom, due to over-heating, especially in summer. The horse tends to lose muscle in its neck and back, despite increased appetite and eating more, while developing a pendulous abdomen. Diabetes often develops, with an associated increase in water consumption and urination. Laminitis always develops eventually. The horse becomes more prone to infections and slower to heal from external injuries due to a depressed immune system. The natural depressions above the eyes tend to fill in with fat.
Any of these symptoms can be caused by a variety of illnesses other than ECD. Consequently, blood and urine tests are normally used to confirm that the cause is ECD (e.g. by measuring hormone levels and hormone response levels) and to rule out other possible diseases. Studies have shown that many horses with ECD are either not diagnosed or incorrectly diagnosed (the symptoms are incorrectly attributed to a different disease), with the result that they do not receive appropriate treatment.
ECD cannot be cured. However, the hormone levels can be reduced to more normal levels through medication, slowing the progress of the disease. As some of the medications can have serious side effects (e.g. liver disease), one needs to monitor for any such side effects and change the medication accordingly.
One also needs to watch for symptoms of secondary diseases, such as laminitis or diabetes, which are more common in horses with ECD. These need to be treated promptly to prevent them from further damaging the horse's health.
One should also maintain the horse's quality of life by treating any symptoms which make it uncomfortable. For example, if the heavier coat results in the horse becoming too warm, one should clip the coat in spring or summer.
About the Author:
Dr. Douglas Stewart is the owner of Horse Health and author of Cushings Disease in Horses article
